Doctor Strange tampers with a risky forbidden spell that alters time and space and accidentally opens a gateway to the multiverse. Together with the Scarlet Witch and the unflappable Wong, Doctor Strange confronts countless dangers in strange and mysterious alternate realities to attempt to restore a single stable reality. As they travel through myriad different layers of the multiverse, they face down a new yet unsettlingly familiar adversary that they will need help to conquer.