London, the 1920s. Lottie and Rose are two married women who share the misery of empty marriages and decide to rent an Italian castle for the spring to get away. In order to save money, they advertise for two other women to join them. Mrs. Fisher is an elderly widow struggling with a lonely and regimented existence. She jumps at the chance to join the vacation. Lady Caroline Dester is a gorgeous flapper who has been grabbed one too many times and believes that she is sick of men. They arrive in San Salvatore. The seaside Italian castle is drenched in wisteria and sunshine. The women find themselves in a transformative beauty so enchanting that they experience changes in themselves they never thought possible.